منابع مشابه
P component in the synovium in RA and OA 465 _ p -
P component is present in amyloid deposits, normal serum, and normal tissues in relation to elastic fibres. Its pathological role in inflammatory synovitis was investigated. Its distribution was determined immunohistologically in 33 synovia: 15 rheumatoid; seven osteoarthritic; seven traumatic controls; and four infected biopsy specimens. P component was present in two circumscribed distributio...
متن کاملMechanisms of OA/ Imaging Appearance
Osteoarthritis (OA) is the most common form of arthritis, affecting about 15% of persons over 60 years of age. Osteoarthritis is the most common cause of disability and a major source of pain and functional limitations. Up to one-half of people aged 50 and over report knee pain during the course of the year, and a quarter have severe and disabling pain. With the aging population and increasing ...
متن کاملAnatomic Pathology / PATHOLOGY OF THE SYNOVIUM Pathology of the Synovium
Synovium is specialized mesenchymal tissue that is essential for the appropriate function of the locomotor apparatus. It is the site for a series of pathologic processes that are characteristic, and in some cases specific, to this distinctive tissue. In this article, the normal microscopic anatomy of synovium is briefly reviewed. Synovial proliferative disorders, including pigmented villonodula...
متن کاملThe Synovium in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease targeting multiple joints. The synovium is the primary site of the inflammatory process, which if untreated leads to irreversible damage to the adjacent cartilage and bone. It is now well established that autoantibodies that are characteristic of RA, including rheumatoid factor (RF) and anti-citrulluninated protein antibodies (ACPA), are...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2019
ISSN: 1063-4584
DOI: 10.1016/j.joca.2019.02.015